Small Cell Lung Cancer: Causes, Symptoms, and Treatment

Medically reviewed by Achuta Uppu, MD, Internal Medicine. Last reviewed: October 23, 2026.

What kind of doctor treats Small Cell Lung Cancer?

A medical oncologist, a doctor who treats cancer with medicines such as chemotherapy, usually leads treatment. A radiation oncologist, a doctor who treats cancer with radiation, and a pulmonologist, a lung doctor, often help too. A direct primary care or concierge doctor can be a first stop for an evaluation and can refer you to a specialist when needed.

What is small cell lung cancer?

Small cell lung cancer is a type of fast-growing cancer that forms in the tissues of the lung. It is less common than non-small cell lung cancer. The American Cancer Society says about 10% to 15% of all lung cancers are small cell lung cancer. It tends to grow and spread faster than non-small cell lung cancer. In most people, the cancer has already spread beyond the lungs when it is found.

Small cell carcinoma, also called oat cell cancer, is the most common type of small cell lung cancer. Doctors usually split it into two stages. In limited stage, the cancer is in the lung where it started. It may have spread to the area between the lungs or to the lymph nodes above the collarbone. In extensive stage, the cancer has spread beyond that area. It is in other places in the body.

Symptoms

The National Cancer Institute says to check with your doctor if you have:

  • Chest discomfort or pain.
  • A cough that does not go away or gets worse over time.
  • Trouble breathing or wheezing.
  • Blood in sputum, which is mucus coughed up from the lungs.
  • Hoarseness or trouble swallowing.
  • Loss of appetite, weight loss for no known reason, or feeling very tired.
  • Swelling in the face and veins in the neck.

These signs may be caused by small cell lung cancer or by other conditions.

Causes and who gets it

Smoking tobacco now or in the past is the most important risk factor for lung cancer. The risk is greater if you start smoking earlier, smoke more often, and smoke for more years. Other risk factors include secondhand smoke and radon in the home or workplace. Exposure to asbestos, arsenic, chromium, beryllium, nickel, soot, or tar at work also raises the risk. Having risk factors does not mean you will get lung cancer.

How doctors diagnose it

Your doctor will ask about your personal and family health history and do a physical exam. Tests may include a chest x-ray and a CT scan. A CT scan makes detailed pictures of the inside of your body. A biopsy removes a sample of tissue from the tumor so a pathologist can look at it under a microscope for cancer. Staging finds out whether the cancer has spread. Staging tests may include an MRI, a PET scan, and a bone scan.

Treatment

Treatment depends on the stage, your overall health, and your preferences. The American Cancer Society says that if you are healthy enough, you will probably get chemotherapy, which is medicine that kills cancer cells. Chemotherapy drugs used include carboplatin, cisplatin, and etoposide.

For limited stage, treatment may include chemotherapy together with radiation therapy to the chest. Immunotherapy with durvalumab may follow it. Surgery is rarely an option. For extensive stage, treatment may include immunotherapy with atezolizumab or durvalumab plus combination chemotherapy.

Radiation to the brain may also be given to lower the chance that the cancer will spread there. Surgery alone is not often used, because this type of lung cancer is usually found in both lungs.

For most people, current treatments do not cure the cancer. Treatment may cause side effects, so ask your cancer care team what to expect. Joining a clinical trial may be an option.

When to see a doctor

Check with your doctor if you have a cough that does not go away, chest discomfort or pain, trouble breathing, blood in your sputum, hoarseness, trouble swallowing, or weight loss for no known reason.

Call 911 or go to the emergency room if you have severe trouble breathing, chest pain or discomfort that lasts two minutes or more, fainting, or a sudden change in mental status such as confusion.

How a direct primary care or concierge doctor fits in

A direct primary care doctor charges a flat monthly fee instead of billing insurance, while a concierge doctor usually charges more and often works alongside insurance. Either can listen to your symptoms, arrange a first test such as a chest x-ray, and refer you to a cancer team.

Common questions

Can small cell lung cancer be cured?

For most people, no, because current treatments do not cure the cancer, says the National Cancer Institute. The American Cancer Society says it tends to respond well to chemotherapy and radiation, but for most people the cancer will return at some point.

What is the difference between limited-stage and extensive-stage small cell lung cancer?

In limited stage, the cancer is in the lung where it started. It may have spread to the area between the lungs or to lymph nodes above the collarbone. In extensive stage, it has spread to other places in the body.

Is surgery used to treat small cell lung cancer?

Surgery alone is not often used. It may be an option when the cancer is found in one lung and in nearby lymph nodes only.

Sources

  1. National Cancer Institute - Small Cell Lung Cancer Treatment (PDQ) Patient Version
  2. American Cancer Society - Small Cell Lung Cancer Treatment
  3. American Cancer Society - What Is Lung Cancer?

Medical Disclaimer

This content is for general educational and informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment, and reading it does not create a doctor-patient relationship. Always seek the advice of your physician or another qualified health provider with any questions about a medical condition, and never disregard or delay seeking professional advice because of something you read here. If you think you may have a medical emergency, call 911 (or your local emergency number) immediately.